ABSTRACT How the architecture of DNA binding sites dictates the extent of repression of promoters is not well understood. Here. we addressed the importance of the number and information content of the three direct repeats (DRs) in the binding and repression of the icdA promoter by the phosphorylated form of the global Escherichia coli repressor ArcA (ArcA-P). We show that decreasing t... https://www.wearepots.com/product-category/womens-footwear/